Latest Research & Publications

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Dissipation Theory of Aging Framework

The Dissipation Theory of Aging: A Quantitative Analysis Using a Cellular Aging Map

A novel framework proposing aging as a dissipative dynamical process, with AI algorithms to quantify cellular aging map. Using 65+ million cells, we reveal how conservative and dissipative forces shape aging across tissues and time.

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PolyGene model architecture and workflow

Multimodal Learning for Mapping Genotype-Phenotype Dynamics

Introducing PolyGene: A foundation model that simultaneously learns gene expression and phenotypic context to reveal the dynamic relationship between genotype and phenotype. Discover how integrated genetics is revolutionizing our understanding of cellular diversity.

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